- Can histological assessment predict the outcome in interstitial cystitis?
MacDermott JP, Charpied GC, Tesluk H, Stone AR. Br J Urol 1991;67:44-7
• in this retrospective study, the outcome of 39 patients with interstitial cystitis was compared to the histological findings at initial diagnostic bladder biopsy
• the degree of inflammation and fibrosis and the mast cell counts were assessed on each biopsy; the prognostic relevance of the clinical features of age, duration of symptoms, frequency, nocturia, pain and bladder capacity was assessed
• the study showed no statistical correlation between the severity of histological findings at diagnosis and the eventual outcome of the disease.
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